Amylyx Pharmaceuticals Inc

Amylyx Pharmaceuticals Inc

AMLX · NASDAQ · Healthcare / Drug Manufacturers - Specialty & Generic

30.29USD+0.43 (+1.44%)

Price History

Full chart

Market Stats

Previous Close29.86
Open29.66
Day Range28.86 – 30.72
52-Week Range10.83 – 41.14
Volume1.62M
Market Cap3.85B
P/E (TTM)0.00
Forward P/E2.77
EPS-1.39
Dividend Yield0.00%
Beta-0.12
50-Day Avg27.98
200-Day Avg18.04

About

Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases. Further, it develops AMX0318, a GLP-1 receptor antagonist for the treatment of post-bariatric hypoglycemia and other rare diseaees. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

Company Details

  • SectorHealthcare
  • IndustryDrug Manufacturers - Specialty & Generic
  • CEOMr. Joshua B. Cohen
  • Employees136
  • Headquarters55 Cambridge Parkway, Cambridge, MA, United States, 02142, USA
  • Websitehttps://amylyx.com

Leadership

  • Mr. Joshua B. CohenCo-Founder, Co-CEO & Director · b. 1992
  • Mr. Justin B. KleeCo-CEO & Director · b. 1991
  • Mr. James M. Frates M.B.A.Chief Financial Officer · b. 1967
  • Dr. Camille L. Bedrosian M.D.Chief Medical Officer · b. 1953
  • Mr. Tom HolmesChief Technical Operations Officer
  • Ms. Lindsey AllenHead of Investor Relations & Communications
  • Ms. Gina M. Mazzariello J.D.Chief Legal Officer & General Counsel · b. 1972
  • Ms. Linda A. ArsenaultChief Human Resources Officer
  • Ms. Tammy SarnelliGlobal Head of Regulatory Affairs
  • Dr. Machelle Manuel Ph.D.VP & Head of Global Medical Affairs

Financials

Income Statement

Currency: USD2019-12-312020-12-312021-12-312022-12-312023-12-312024-12-312025-12-31
Total Revenue1.43M650.00K285.00K22.23M380.79M87.37M0
Growth (%)--54.42%-56.15%+7700.00%+1612.94%-77.06%-100.00%
Cost of Revenue11.90M24.59M52.00K2.99M25.44M42.16M525.00K
Gross Profit-10.47M-23.94M285.00K19.24M355.35M45.22M-525.00K
Gross Margin-734.43%-3683.69%100.00%86.54%93.32%51.75%-
Operating Expense3.08M15.06M82.97M220.58M316.54M359.95M152.77M
Operating Income-13.55M-39.01M-82.69M-201.34M38.80M-314.73M-153.29M
Operating Margin-950.49%-6000.77%-29013.33%-905.72%10.19%-360.22%-
EBITDA1.11M-39.00M-82.64M-200.85M55.38M-290.98M-144.16M
EBITDA Margin78.12%-6000.62%-28995.09%-903.53%14.54%-333.03%-
Net Income-14.82M-42.28M-87.88M-198.38M49.27M-301.74M-144.74M
Net Income Margin-1038.99%-6504.62%-30834.74%-892.38%12.94%-345.36%-
R&D11.90M24.59M44.04M93.45M128.19M104.08M90.40M
R&D as % of Total Revenue834.43%3783.69%15452.63%420.38%33.66%119.13%-
Interest Expense1.28M2.29M36.00K4.29M---
Interest Expense % of Total Revenue89.48%352.00%12.63%19.30%---

Balance Sheet

Currency: USD2019-12-312020-12-312021-12-312022-12-312023-12-312024-12-312025-12-31
Total Assets3.22M14.10M105.61M391.45M517.45M193.63M332.64M
Total Liabilities28.58M80.83M256.78M50.85M84.02M28.87M27.39M
Total Equity-25.36M-66.72M-151.17M340.61M433.43M164.76M305.26M
Cash3.06M12.88M50.19M62.53M170.20M77.39M226.65M
Total Debt14.93M1.43M-6.28M4.24M1.98M5.96M
Net Debt11.87M-11.45M-50.19M-56.25M-165.96M-75.41M-220.69M

Cash Flow

Currency: USD2019-12-312020-12-312021-12-312022-12-312023-12-312024-12-312025-12-31
Operating Cash Flow-10.69M-36.70M-74.80M-179.87M11.92M-167.65M-123.34M
Investing Cash Flow-151.00K-151.00K-46.41M-238.99M92.05M75.65M14.04M
Financing Cash Flow668.00K46.82M158.51M431.79M3.54M348.00K257.03M
Capital Expenditure151.00K151.00K353.00K2.53M1.24M157.00K138.00K
Free Cash Flow-10.69M-36.85M-75.15M-182.40M10.68M-167.80M-123.48M
FCF to OCF100.00%100.41%100.47%101.40%89.59%100.09%100.11%

Earnings

Report DateDec 1, 2021Mar 30, 2022May 12, 2022Aug 11, 2022Nov 10, 2022Mar 13, 2023May 11, 2023Aug 10, 2023Nov 9, 2023Feb 22, 2024May 9, 2024Aug 8, 2024Nov 7, 2024Mar 4, 2025May 8, 2025Aug 7, 2025Nov 6, 2025Mar 3, 2026May 7, 2026Aug 6, 2026Nov 5, 2026
EPS Estimate-5.52-0.64-0.69-0.84-0.98-0.82-0.250.070.440.23-0.01-0.82-0.91-0.56-0.50-0.44-0.43-0.34-0.34-0.36-0.38
EPS Actual-3.81-4.15-0.93-0.93-0.92-0.650.020.310.300.07-0.12-0.62-1.07-0.55-0.42-0.46-0.37-0.30-0.37-0.39-
Surprise30.98%-548.44%-34.78%-10.71%6.12%20.73%108.00%342.86%-31.82%-69.57%-1100.00%24.39%-17.58%1.79%16.00%-4.55%13.95%11.76%-8.82%-8.33%-
Timing-After-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursPre-marketPre-marketPre-marketPre-marketPre-market-Pre-marketPre-marketPre-marketPre-marketPre-marketPre-marketPre-market

Key Statistics & Ratios

Market Cap3.85B
Enterprise Value3.90B
Trailing P/E0.00
Forward P/E2.77
Price / Sales0.66
Price / Book17.32
EPS-1.39
Book Value2.15
Revenue (TTM)-665.00K
Gross Profit (TTM)-92.45M
EBITDA-161.73M
Profit Margin0.00%
Operating Margin0.00%
Return on Equity-74.73%
Return on Assets-44.13%
Shares Outstanding127.63M
Shares Float97.25M
Beta-0.12
Dividend Yield0.00%
Dividend Rate0.00
Payout Ratio0.00%

Analyst Ratings

Strong Buy
Based on 7 analystsTarget 42.36
  • Strong Buy
    5
  • Buy
    1
  • Hold
    1

Ownership Breakdown

Institutions
94.13%
Insiders
7.18%
Retail / Other
0.00%

Top Institutional Holders

  • FMR Inc
    16.63M14.93%
  • BlackRock Inc
    8.83M7.92%
  • Perceptive Advisors LLC
    8.33M7.48%
  • TCG Crossover Management, LLC
    6.24M5.60%
  • COMMODORE CAPITAL LP
    5.65M5.07%
  • HHG PLC
    4.99M4.47%
  • Saturn V Capital Management LLC
    4.62M4.15%
  • Vanguard Capital Management, LLC
    4.14M3.72%
  • First Light Asset Management, LLC
    3.02M2.71%
  • Driehaus Capital Management LLC
    2.99M2.68%
  • The Goldman Sachs Group Inc
    2.63M2.36%
  • State Street Corp
    2.36M2.12%
  • Franklin Templeton Inc
    2.26M2.03%
  • Geode Capital Management, LLC
    2.21M1.98%
  • Morgan Stanley - Brokerage Accounts
    2.18M1.95%
  • Almitas Capital LLC
    2.12M1.91%
  • Adage Capital Partners Gp LLC
    1.90M1.71%

Top Fund Holders

  • Vanguard MStar Total Stk Mkt Idx Invest
    3.79M3.02%
  • iShares Russell 2000 ETF
    2.57M2.05%
  • Fidelity Advisor Biotechnology I
    2.43M1.94%