Iovance Biotherapeutics Inc

Iovance Biotherapeutics Inc

IOVA · NASDAQ · Healthcare / Biotechnology

7.76USD+0.13 (+1.70%)

Price History

Full chart

Market Stats

Previous Close7.63
Open7.80
Day Range7.46 – 7.83
52-Week Range1.76 – 15.37
Volume11.67M
Market Cap6.71B
P/E (TTM)0.00
Forward P/E0.00
EPS-0.69
Dividend Yield0.00%
Beta0.76
50-Day Avg11.35
200-Day Avg5.77

About

Iovance Biotherapeutics, Inc., a commercial-stage biopharmaceutical company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States and internationally. The company offers Amtagvi, an individualized T cell therapy for solid tumor cancer and for the treatment of adult patients with previously treated advanced, or unresectable or metastatic melanomal; and Proleukin, an interleukin-2 product for the treatment of patients with metastatic melanoma and metastatic renal cell carcinoma. It also develops lifileucel for the treatment of melanoma, cervical cancer, non-small cell lung cancer (NSCLC), endometrial cancer, and head and neck squamous cell carcinoma (HNSCC); LN-145-S1 to treat melanoma and HNSCC; LN-145 Gen 3 and core biopsy for the treatment of NSCLC; LN-145 Gen 3 to treat melanoma and HNSCC; IOV-2001 to treat chronic lymphocytic leukemia and small lymphocytic lymphoma; IOV-4001 for the treatment of melanoma and NSCLC; and IOV-3001 for use in the TIL therapy treatment regimen. The company has collaborations and licensing agreements with National Institutes of Health; the National Cancer Institute; Cellectis S.A.; Novartis Pharma AG; and Boehringer Ingelheim Biopharmaceuticals GmbH. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in San Carlos, California.

Company Details

  • SectorHealthcare
  • IndustryBiotechnology
  • CEODr. Frederick G. Vogt Esq., J.D., Ph.D.
  • Employees975
  • Headquarters300 Rouse Blvd., Philadelphia, PA, United States, 19112, USA
  • Websitehttps://www.iovance.com

Leadership

  • Dr. Frederick G. Vogt Esq., J.D., Ph.D.Interim CEO, President, General Counsel, Corporate Secretary & Director · b. 1974
  • Ms. Corleen M. RocheChief Financial Officer · b. 1966
  • Dr. Igor P. Bilinsky Ph.D.Chief Operating Officer · b. 1973
  • Dr. Raj K. Puri M.D., Ph.D.Chief Regulatory Officer · b. 1956
  • Mr. Daniel G. KirbyChief Commercial Officer · b. 1972
  • Ms. Sara PellegrinoSenior Vice President of Investor Relations & Corporate Communications
  • Ms. Tracy WintonExecutive Vice President of Human Resources
  • Mr. Howard B. Johnson M.B.A.Chief Business Officer · b. 1960
  • Mr. Kevin SmythExecutive Vice President of Quality
  • Dr. Brian Gastman M.D.Executive Vice President of Translational Medicine & Research

Financials

Income Statement

Currency: USD2008-12-312009-12-312010-12-312011-12-312012-12-312013-12-312014-12-312015-12-312016-12-312017-12-312018-12-312019-12-312020-12-312021-12-312022-12-312023-12-312024-12-312025-12-31
Total Revenue---00000000000238.00K1.19M164.07M263.50M
Growth (%)---------------+399.58%+13698.99%+60.60%
Cost of Revenue-1.33K-19.30M04.66M88.22K999.00K978.00K952.00K956.00K8.12M8.71M13.98M21.14M10.76M124.00M173.18M
Gross Profit----19.30M0-4.66M-9.34M-999.00K-978.00K-952.00K-956.00K-8.12M-8.71M-13.98M-21.14M-9.57M40.08M90.32M
Gross Margin---------------8880.25%-804.54%24.43%34.28%
Operating Expense---1.92M8.13M17.99M2.70M26.86M52.66M91.92M127.30M198.75M253.22M328.72M377.74M450.99M435.35M488.53M
Operating Income-57.14K-15.77K-815.00K-21.22M-8.13M-22.64M-12.04M-27.86M-53.64M-92.88M-128.26M-206.87M-261.94M-342.70M-398.88M-460.56M-395.28M-398.21M
Operating Margin---------------167595.80%-38734.99%-240.92%-151.12%
EBITDA-55.81K-14.44K-1.55M-20.54M-8.13M-24.93M-11.95M-26.86M-52.66M-91.92M-127.30M-205.70M-260.80M-328.72M-377.74M-414.39M-331.40M-350.89M
EBITDA Margin---------------158715.55%-34851.89%-201.99%-133.16%
Net Income-57.14K-15.77K-1.61M-25.69M-3.31M-25.38M-12.04M-27.66M-52.89M-92.06M-123.58M-187.07M-259.58M-327.82M-389.92M-444.04M-372.18M-390.98M
Net Income Margin---------------163833.19%-37345.42%-226.84%-148.38%
R&D---1.76M1.66M1.33M2.71M15.47M28.04M71.61M99.83M166.02M201.73M259.04M294.78M344.08M282.34M300.27M
R&D as % of Total Revenue--------------123857.56%28938.35%172.08%113.95%
Interest Expense000151.51K0444.73K5.66K200.00K00002.36M451.00K2.98M---
Interest Expense % of Total Revenue--------------1254.20%---

Balance Sheet

Currency: USD2008-12-312009-12-312010-12-312011-12-312012-12-312013-12-312014-12-312015-12-312016-12-312017-12-312018-12-312019-12-312020-12-312021-12-312022-12-312023-12-312024-12-312025-12-31
Total Assets5.61K9.63K1.46M568.43K29.41K19.87M46.51M105.65M171.89M155.37M480.82M344.65M768.46M777.33M663.98M780.35M910.43M913.17M
Total Liabilities3.33K23.12K822.87K13.35M11.35M2.27M1.66M1.63M4.97M9.89M14.63M45.68M111.96M155.67M164.34M195.74M200.02M214.59M
Total Equity2.28K-13.49K638.09K-12.78M-11.32M17.60M44.85M104.02M166.92M145.48M466.19M298.97M656.50M621.66M499.64M584.61M710.40M698.58M
Cash2.90K8.26K1.30M510.22K019.67M44.91M103.70M166.47M145.37M82.15M13.97M67.33M78.23M231.73M114.89M115.69M163.08M
Total Debt---5.00M6.48M6.48M-----11.50M51.66M71.53M85.45M75.86M58.26M48.44M
Net Debt-2.90K-8.26K-1.30M4.49M6.48M-19.67M-44.91M-103.70M-166.47M-145.37M-82.15M-2.47M-15.67M-6.70M-146.28M-39.03M-57.43M-114.63M

Cash Flow

Currency: USD2008-12-312009-12-312010-12-312011-12-312012-12-312013-12-312014-12-312015-12-312016-12-312017-12-312018-12-312019-12-312020-12-312021-12-312022-12-312023-12-312024-12-312025-12-31
Operating Cash Flow-57.30K-14.45K-620.80K-6.19M-2.24M-3.66M-8.63M-18.38M-32.67M-78.71M-101.25M-158.89M-205.13M-227.94M-292.76M-361.82M-352.98M-302.41M
Investing Cash Flow----81.05K0-12.71K-1.59M-91.15M8.89M58.68M-386.28M90.03M-317.85M132.00K256.45M-155.24M-96.41M47.50M
Financing Cash Flow-19.80K1.91M5.49M1.73M23.35M35.46M78.27M96.90M58.69M424.31M6.13M576.42M239.27M190.15M462.96M390.66M300.77M
Capital Expenditure00031.05K012.71K1.59M1.14M1.52M1.03M1.20M6.92M46.79M37.57M20.43M22.29M11.07M33.84M
Free Cash Flow-57.30K-14.45K-620.80K-6.22M-2.24M-3.67M-10.23M-19.52M-34.19M-79.74M-102.45M-165.81M-251.93M-265.51M-313.18M-384.11M-364.05M-336.24M
Dividends Paid---0000049.45M0---1.00M----
FCF to OCF100.00%100.00%100.00%100.50%100.00%100.35%118.44%106.22%104.66%101.31%101.18%104.35%122.81%116.48%106.98%106.16%103.14%111.19%
Dividend Paid to FCF---0.00%0.00%0.00%0.00%0.00%-144.65%0.00%----0.38%----

Earnings

Report DateSep 30, 2009Dec 31, 2009Mar 31, 2010Jun 30, 2010Sep 30, 2010Dec 31, 2010Mar 31, 2011Jun 30, 2011Sep 30, 2011Dec 31, 2011Mar 31, 2012Jun 30, 2012Sep 30, 2012Dec 31, 2012Mar 31, 2013Aug 28, 2013Nov 27, 2013Mar 28, 2014May 14, 2014Aug 8, 2014Nov 13, 2014Mar 16, 2015May 11, 2015Aug 10, 2015Nov 5, 2015Mar 10, 2016May 9, 2016Aug 8, 2016Nov 4, 2016Mar 7, 2017May 1, 2017Aug 1, 2017Oct 31, 2017Mar 12, 2018May 10, 2018Aug 6, 2018Nov 6, 2018Feb 27, 2019May 7, 2019Aug 1, 2019Nov 4, 2019Feb 25, 2020May 5, 2020Aug 6, 2020Nov 5, 2020Feb 25, 2021May 6, 2021Aug 5, 2021Nov 4, 2021Feb 24, 2022May 5, 2022Aug 4, 2022Nov 3, 2022Feb 28, 2023May 9, 2023Aug 8, 2023Nov 7, 2023Feb 28, 2024May 9, 2024Aug 8, 2024Nov 7, 2024Feb 26, 2025May 8, 2025Aug 7, 2025Nov 6, 2025Feb 24, 2026Mar 31, 2026Aug 6, 2026Nov 5, 2026
EPS Estimate------------------0.11-0.09-0.11-0.10-0.09-0.11-0.11-0.16-0.20-0.25-0.20-0.16-0.25-0.27-0.28-0.29-0.32-0.29-0.32-0.33-0.26-0.29-0.29-0.39-0.42-0.51-0.52-0.46-0.44-0.49-0.51-0.53-0.56-0.63-0.61-0.64-0.64-0.73-0.79-0.46-0.43-0.42-0.35-0.30-0.27-0.24-0.29-0.26-0.18-0.15-0.17-0.09
EPS Actual-0.00-0.00-0.00-0.12-0.99-1.14-0.78-14.80-7.43-11.00-7.39-0.42-0.864.23-1.28-54.94-0.66-1.50-0.11-0.09-0.11-0.18-0.14-0.14-0.16-0.20-0.14-0.23-0.17-0.25-0.28-0.37-0.35-0.32-0.31-0.34-0.36-0.27-0.30-0.38-0.40-0.50-0.55-0.47-0.40-0.47-0.51-0.53-0.55-0.63-0.58-0.63-0.63-0.64-0.50-0.47-0.46-0.45-0.42-0.34-0.28-0.26-0.36-0.33-0.25-0.18-0.19-0.11-
Surprise------------------1263.64%-22.22%18.18%-10.00%-100.00%-27.27%-27.27%0.00%0.00%44.00%-15.00%-6.25%0.00%-3.70%-32.14%-20.69%0.00%-6.90%-6.25%-9.09%-3.85%-3.45%-31.03%-2.56%-19.05%-7.84%9.62%13.04%-6.82%-4.08%-3.92%-3.77%-12.50%7.94%-3.28%1.56%0.00%31.51%40.51%0.00%-4.65%0.00%2.86%6.67%2.84%-50.00%-13.79%3.85%0.00%-23.78%35.29%-
Timing------------------After-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursPre-marketPre-marketPre-marketAfter-hoursPre-marketAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursAfter-hoursPre-marketAfter-hoursAfter-hoursPre-marketPre-market-Pre-marketPre-market

Key Statistics & Ratios

Market Cap6.71B
Enterprise Value6.65B
Trailing P/E0.00
Forward P/E0.00
PEG Ratio0.00
Price / Sales20.64
Price / Book9.14
EPS-0.69
Book Value1.63
Revenue (TTM)324.97M
Gross Profit (TTM)157.29M
EBITDA-259.60M
Profit Margin-89.09%
Operating Margin-52.26%
Return on Equity-40.36%
Return on Assets-20.31%
Shares Outstanding452.97M
Shares Float394.31M
Beta0.76
Dividend Yield0.00%
Dividend Rate0.00
Payout Ratio0.00%

Analyst Ratings

Buy
Based on 10 analystsTarget 14.40
  • Strong Buy
    6
  • Buy
    2
  • Hold
    2

Ownership Breakdown

Institutions
70.73%
Insiders
0.35%
Retail / Other
28.92%

Top Institutional Holders

  • BlackRock Inc
    36.96M8.16%
  • Mhr Fund Management Llc
    28.97M6.39%
  • State Street Corp
    24.48M5.40%
  • Two Sigma Investments LLC
    19.01M4.20%
  • Vanguard Capital Management, LLC
    18.20M4.02%
  • Vanguard Portfolio Management, LLC
    14.39M3.18%
  • Geode Capital Management, LLC
    10.32M2.28%
  • Millennium Management LLC
    8.53M1.88%
  • Dimensional Fund Advisors, Inc.
    6.46M1.43%
  • Palo Alto Investors, LLC
    5.30M1.17%
  • The Goldman Sachs Group Inc
    5.10M1.13%
  • Nuveen, LLC
    5.00M1.10%
  • Bank of America Corp
    4.99M1.10%
  • Morgan Stanley - Brokerage Accounts
    4.99M1.10%
  • Jupiter Asset Management Limited
    4.54M1.00%
  • Jane Street Group LLC
    4.39M0.97%

Top Fund Holders

  • Vanguard MStar Total Stk Mkt Idx Invest
    13.55M2.99%
  • State Street® SPDR® S&P® Biotech ETF
    11.32M2.50%
  • iShares Russell 2000 ETF
    10.29M2.27%
  • Vanguard Small Cap Index
    4.85M1.07%

Stock Splits

  • Sep 26, 20131:100
  • May 26, 201023999:1000